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Vildagliptin 維達列汀

規格: 95%

CAS: 274901-16-5

產品編號: H66251

MDL: MFCD09952339

品牌: INFI

Chemical Name	(S)-1-[2-[(3-Hydroxyadamant-1-yl)amino]acetyl]pyrrolidine-2-carbonitrile
CAS Number	274901-16-5
Synonym	(2S)-
Chemical Name Translation	(2S)-1-((3-羥基三環[3.3.1.1[3,7]]癸烷-1-基)氨基)乙酰基)吡咯烷-2-腈
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Packing Group	III

It is a new oral anti-hyperglycemic agent of a new dipeptidyl peptidase-IV (DPP-IV) inhibitor class of drugs. Antidiabetic.

{MCE} [2]. Wu YJ, et al. Dipeptidyl peptidase-4 inhibitor, vildagliptin, inhibits pancreatic beta cell apoptosis in associationwith its effects suppressing endoplasmic reticulum stress in db/db mice. Metabolism. 2015 Feb;64(2):226-35.

{TRC} Ahren, B., et al.: Diabetes Care, 27, 2874 (2004),

{TRC} Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004),

{TRC} Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),

{MCE} [1]. Villhauer EB, et al. 1-[[(3-hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties. J Med Chem. 2003 Jun 19;46(13):2774-89.

{MCE} [2]. Wu YJ, et al. Dipeptidyl peptidase-4 in

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化學屬性

Mol. Formula	C17H25N3O2
Mol. Weight	303
Density	1.27
Boiling Point	531.3

*以上化合物性質及應用等信息僅供參考

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Vildagliptin 維達列汀

規格: 95%

化學屬性